Thursday March 7, 2019
12:00 pm – 1:30 pm EST
Instructor: J. Jeff Schwegman, Ph.D.
Over the years, scientists have strived to understand and apply scientific principles to the formulation and process development of freeze-dried products. As opposed to using a “trial and error” approach, modern formulation and process development scientists have the information and tools necessary to design an optimal formulation and lyophilization cycle using a scientifically based empirical approach. By understanding the scientific principles and physical properties of the formulation and the lyophilization process, the development scientist can design a product that is produced in the most cost effective manner, in the least amount of time, is of the highest quality, and has adequate long term stability. Additionally, there have been many new and exciting technologies on the horizon, or in the early stages of implementation, in freeze-drying equipment. Several of these new technologies will be discussed in regards to both production-scale and development-scale freeze-dryers, and details on the advantages and or disadvantages of each will be discussed.
You will learn:
- How to characterize your formulation (DSC & Freeze-Dry Microscopy)
- How to determine the critical temperatures of your formulation (glass transitions and eutectic melting temperatures)
- How to use the thermal properties to optimize your cycle
- New techniques and technologies for improving your cycles
- Tips for troubleshooting failed lyophilization cycles or products
Fee:
$385 for one person
$700 2-5 people
$999 6-10 people
Questions? support@eccwebinars.com
ECC-096